ICPRAM 2021 (10th International Conference on Pattern Recognition Applications and Methods) received 97 paper submissions from 30 countries. To evaluate each submission, a double‐blind paper review was performed by the Program Committee. After a stringent selection process, 21 papers were published and presented as full papers, i.e. completed work (12 pages/25' oral presentation), 53 papers were accepted as short papers (28 as oral presentation and 25 as poster presentation). ICPRAM's program included three invited talks delivered by internationally distinguished speakers, namely: The papers were organized in thirteen parallel sessions ranging from areas such as Machine Learning Methods; Deep Learning and Neural Networks; Classification and Clustering; Natural Language Processing; Theory and Methods; Methods and Applications; and Image and Video Analysis and Understanding. The organizing committee included the ICPRAM Conference Chair: Ana Fred, Instituto de Telecomunicações and University of Lisbon, Portugal; and the Program Co‐Chairs: Maria De Marsico, Sapienza Università di Roma, Italy; and Gabriella Sanniti di Baja, Italian National Research Council CNR, Italy.